Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 22 Researches
7.4
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
250 mg
278%
Vitamin E (as d-alpha Tocopheryl Succinate)
20 mg
133%
Alpha Lipoic Acid
100 mg
†
Top Medical Research Studies
9
Potential atheroprotective effects of T3
We aimed to explore how pure tocotrienol (T3), a form of vitamin E, might help in fighting atherosclerosis, a condition often linked to high cholesterol. In our study, 30 rabbits were fed high-cholesterol diets and then divided into groups receiving different doses of T3 or a control without T3.
The results were promising, showing that the lower and higher doses of T3 significantly reduced atherosclerotic markers and inflammation in early and established atherosclerosis compared to the control group. This suggests that T3 may play a valuable role alongside standard treatments in preventing coronary artery disease.
The results were promising, showing that the lower and higher doses of T3 significantly reduced atherosclerotic markers and inflammation in early and established atherosclerosis compared to the control group. This suggests that T3 may play a valuable role alongside standard treatments in preventing coronary artery disease.
Read More
9
Vitamin C reduces cholesterol levels
We explored how vitamin C supplementation affects cholesterol levels in broiler chickens, particularly under heat stress conditions. Through a thorough meta-analysis of 35 studies conducted between 1985 and 2023, we assessed various performance metrics, including blood parameters, carcass characteristics, and overall meat quality.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
Read More
8
Tocopheryl quinone benefits high cholesterol
We examined how tocopheryl quinone, a form of vitamin E, impacts high cholesterol in rats fed a high-fat diet linked to liver disease. Our findings showed that while these rats had increased cholesterol levels, tocopheryl quinone treatment was able to reverse these effects.
We noted improvements in gut health and reductions in harmful inflammatory markers after treatment. However, the study focused on a specific animal model, so results may not directly apply to humans.
Overall, tocopheryl quinone appears promising in addressing cholesterol issues related to liver complications.
We noted improvements in gut health and reductions in harmful inflammatory markers after treatment. However, the study focused on a specific animal model, so results may not directly apply to humans.
Overall, tocopheryl quinone appears promising in addressing cholesterol issues related to liver complications.
Read More
Most Useful Reviews
9
Reduced bad cholesterol
51 people found this helpful
A wonderful dietary supplement for various bodily processes. Test results showed a decrease in bad cholesterol levels.
Read More
7.5
Positive impact observed
2 people found this helpful
I began taking this based on a recommendation following my gestational diabetes diagnosis. So far, it appears to have a positive impact and is yet another high-quality product from this brand.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 22 Researches
7.4
- All Researches
9
Vitamin C reduces cholesterol levels
We explored how vitamin C supplementation affects cholesterol levels in broiler chickens, particularly under heat stress conditions. Through a thorough meta-analysis of 35 studies conducted between 1985 and 2023, we assessed various performance metrics, including blood parameters, carcass characteristics, and overall meat quality.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
Read More
9
We conducted a study to explore how vitamin C, combined with chromium, affects high cholesterol levels in patients with type 2 diabetes. This interesting research involved 60 participants, evenly split between a treatment group receiving vitamin C (500mg) and chromium (200µg), and a control group taking a placebo.
Our analysis revealed notable reductions in several important lipid measurements within the treatment group. Specifically, we observed a significant drop in total cholesterol and improvements in High-Density Lipoprotein (HDL), Low-Density Lipoprotein (LDL), and triglyceride levels.
The results illuminate the potential benefits of vitamin C and chromium in managing cholesterol levels for those impacted by type 2 diabetes. While this study doesn't focus solely on vitamin C, the combined effects of both supplements indicate a promising avenue for improving lipid profiles and overall health in diabetic patients.
Our analysis revealed notable reductions in several important lipid measurements within the treatment group. Specifically, we observed a significant drop in total cholesterol and improvements in High-Density Lipoprotein (HDL), Low-Density Lipoprotein (LDL), and triglyceride levels.
The results illuminate the potential benefits of vitamin C and chromium in managing cholesterol levels for those impacted by type 2 diabetes. While this study doesn't focus solely on vitamin C, the combined effects of both supplements indicate a promising avenue for improving lipid profiles and overall health in diabetic patients.
Read More
9
To explore the impact of vitamin C on high cholesterol levels, we designed a study involving 106 young male athletes. They were divided into five groups, including those who did not exercise and those who underwent high-intensity interval training (HIIT), some with added vitamin C, vitamin E, or both. Over eight weeks, we assessed changes in lipid profiles and various blood variables.
Our findings were promising for those taking vitamins C and E alongside regular exercise. Participants who supplemented with these vitamins and engaged in HIIT showed significant drops in body weight, overall fat percentage, total cholesterol, and triglycerides. Remarkably, levels of high-density lipoprotein cholesterol, often dubbed "good cholesterol," increased in all four intervention groups. This suggests a potential role for vitamin C in improving cholesterol levels, especially when paired with an active lifestyle.
However, we also noted some adverse changes—specifically, reductions in certain blood cell counts among those only doing HIIT. While the vitamin-supplemented groups did experience effective elevation in beneficial vitamin levels, the overall effects of vitamin C alone on high cholesterol were less definitive, as the benefits appeared more in combination with exercise. It's safe to say that although vitamin C shows some promise in reducing cholesterol, the strongest benefits occur when it's part of a broader healthy regimen.
Our findings were promising for those taking vitamins C and E alongside regular exercise. Participants who supplemented with these vitamins and engaged in HIIT showed significant drops in body weight, overall fat percentage, total cholesterol, and triglycerides. Remarkably, levels of high-density lipoprotein cholesterol, often dubbed "good cholesterol," increased in all four intervention groups. This suggests a potential role for vitamin C in improving cholesterol levels, especially when paired with an active lifestyle.
However, we also noted some adverse changes—specifically, reductions in certain blood cell counts among those only doing HIIT. While the vitamin-supplemented groups did experience effective elevation in beneficial vitamin levels, the overall effects of vitamin C alone on high cholesterol were less definitive, as the benefits appeared more in combination with exercise. It's safe to say that although vitamin C shows some promise in reducing cholesterol, the strongest benefits occur when it's part of a broader healthy regimen.
Read More
9
Potential atheroprotective effects of T3
We aimed to explore how pure tocotrienol (T3), a form of vitamin E, might help in fighting atherosclerosis, a condition often linked to high cholesterol. In our study, 30 rabbits were fed high-cholesterol diets and then divided into groups receiving different doses of T3 or a control without T3.
The results were promising, showing that the lower and higher doses of T3 significantly reduced atherosclerotic markers and inflammation in early and established atherosclerosis compared to the control group. This suggests that T3 may play a valuable role alongside standard treatments in preventing coronary artery disease.
The results were promising, showing that the lower and higher doses of T3 significantly reduced atherosclerotic markers and inflammation in early and established atherosclerosis compared to the control group. This suggests that T3 may play a valuable role alongside standard treatments in preventing coronary artery disease.
Read More
8
We investigated how a high cholesterol diet impacts male fertility by activating stress in testicular cells, leading to cell death. Using rabbits as our model, we found that this diet noticeably increased apoptosis in the testicular tubules. However, when we supplemented the rabbits' diets with α-tocopherol, a form of vitamin E, we observed a remarkable reduction in this cholesterol-induced cell death. This suggests that vitamin E might serve as a protective agent against damage caused by high cholesterol, helping to preserve testicular health.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Reduced bad cholesterol
51 people found this helpful
A wonderful dietary supplement for various bodily processes. Test results showed a decrease in bad cholesterol levels.
Read More
7.5
Positive impact observed
2 people found this helpful
I began taking this based on a recommendation following my gestational diabetes diagnosis. So far, it appears to have a positive impact and is yet another high-quality product from this brand.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Tavakolinasab F, Hashemi M. Effect of Using Vitamin C Supplementation on Performance, Blood Parameters, Carcass Characteristics and Meat Quality of Broiler Chickens Under Heat Stress Condition: A Meta-Analysis. J Anim Physiol Anim Nutr (Berl). 2025. doi:10.1111/jpn.14091
- Sabar N, Hussain MI, Saleem H, Khan MA, Khalid H, et al. Synchronizing positive effect of vitamin C and chromium on hyper lipidemia, hyperglycemia, liver enzymes and BMI of diabetes mellitus type 2 patients. Pak J Pharm Sci. 2024;37:199.
- Son J, Lee WD, Kim H, Hong EC, Kim HJ, et al. A comparative study on feeding timing and additive types of broilers in a high-temperature environment. J Anim Sci. 2023;101. doi:10.1093/jas/skad290
- Sarkar S, Dey SK, Datta G, Bandyopadhyay A. Vitamin C and E supplementation and high intensity interval training induced changes in lipid profile and haematological variables of young males. Sports Med Health Sci. 2023;5:137. doi:10.1016/j.smhs.2023.03.006
- Darand M, Salehi-Abargouei A, Vahidi Mehrjardi MY, Feizi A, Seyedhossaini SM, et al. Joint effects of paraoxonase 1 rs662 polymorphism and vitamins C/E intake on coronary artery disease severity (Gensini and SYNTAX scores) and lipid profile in patients undergoing coronary angiography. Front Nutr. 2022;9:1097411. doi:10.3389/fnut.2022.1097411
- Omidi S, Bouyeh M, Seidavi A. The effect of vitamin C and aspirin supplementation on the performance of turkeys under normal conditions. Anim Biotechnol. 2023;34:3395. doi:10.1080/10495398.2022.2152037
- Sozen E, Demirel-Yalciner T, Koroglu MK, Elmas MA, Ercan F, et al. High cholesterol diet activates ER stress mediated apoptosis in testes tissue: Role of α-tocopherol. IUBMB Life. 2022;74:85. doi:10.1002/iub.2535
- Sun T, Zhang B, Ru QJ, Chen XM, Lv BD. Tocopheryl quinone improves non-alcoholic steatohepatitis (NASH) associated dysmetabolism of glucose and lipids by upregulating the expression of glucagon-like peptide 1 (GLP-1) restoring the balance of intestinal flora in rats. Pharm Biol. 2021;59:723. doi:10.1080/13880209.2021.1916542
- Demirel-Yalciner T, Sozen E, Ozaltin E, Sahin A, Ozer NK. alpha-Tocopherol supplementation reduces inflammation and apoptosis in high cholesterol mediated nonalcoholic steatohepatitis. Biofactors. 2021;47:403. doi:10.1002/biof.1700
- Bozaykut P, Ekren R, Sezerman OU, Gladyshev VN, Ozer NK. High-throughput profiling reveals perturbation of endoplasmic reticulum stress-related genes in atherosclerosis induced by high-cholesterol diet and the protective role of vitamin E. Biofactors. 2020;46:653. doi:10.1002/biof.1635
- Sarkisova EA, Chumak AA, Ovsyannikova LM, Alekhina LM, Nosach OV, et al. THE EFFECT OF APPLICATION OF ANTIOXIDANT THERAPY IN THE TREATMENT OF NON-ALKOHOLIC STEATOHEPATATIS IN CHORNOBYL NPP ACCIDENT SUFFERERS IN THE REMOTE PERIOD AFTER IRRADIATION. Probl Radiac Med Radiobiol. 2018;23:452. doi:10.33145/2304-8336-2018-23-452-461
- Sozen E, Yazgan B, Sahin A, Ince U, Ozer NK. High Cholesterol Diet-Induced Changes in Oxysterol and Scavenger Receptor Levels in Heart Tissue. Oxid Med Cell Longev. 2018;2018:8520746. doi:10.1155/2018/8520746
- Farràs M, Fernández-Castillejo S, Rubió L, Arranz S, Catalán Ú, et al. Phenol-enriched olive oils improve HDL antioxidant content in hypercholesterolemic subjects. A randomized, double-blind, cross-over, controlled trial. J Nutr Biochem. 2018;51:99. doi:10.1016/j.jnutbio.2017.09.010
- Libinaki R, Vinh A, Tesanovic-Klajic S, Widdop R, Gaspari T. The effect of tocopheryl phosphates (TPM) on the development of atherosclerosis in apolipoprotein-E deficient mice. Clin Exp Pharmacol Physiol. 2017;44 Suppl 1:107. doi:10.1111/1440-1681.12821
- Rahman TA, Hassim NF, Zulkafli N, Muid S, Kornain NK, et al. Atheroprotective effects of pure tocotrienol supplementation in the treatment of rabbits with experimentally induced early and established atherosclerosis. Food Nutr Res. 2016;60:31525. doi:10.3402/fnr.v60.31525
- Bumrungpert A, Pavadhgul P, Kalpravidh RW. Camellia Oil-Enriched Diet Attenuates Oxidative Stress and Inflammatory Markers in Hypercholesterolemic Subjects. J Med Food. 2016;19:895. doi:10.1089/jmf.2016.3659
- Apostolidou C, Adamopoulos K, Lymperaki E, Iliadis S, Papapreponis P, et al. Cardiovascular risk and benefits from antioxidant dietary intervention with red wine in asymptomatic hypercholesterolemics. Clin Nutr ESPEN. 2015;10:e224. doi:10.1016/j.clnesp.2015.08.001
- Katsarou AI, Kaliora AC, Chiou A, Kalogeropoulos N, Papalois A, et al. Amelioration of oxidative and inflammatory status in hearts of cholesterol-fed rats supplemented with oils or oil-products with extra virgin olive oil components. Eur J Nutr. 2016;55:1283. doi:10.1007/s00394-015-0947-5
- Schuchardt JP, Heine S, Hahn A. A combination of palm oil tocotrienols and citrus peel polymethoxylated flavones does not influence elevated LDL cholesterol and high-sensitivity C-reactive protein levels. Eur J Clin Nutr. 2015;69:1209. doi:10.1038/ejcn.2015.44
- Busso D, Mascareño L, Salas F, Berkowitz L, Santander N, et al. Early onset intrauterine growth restriction in a mouse model of gestational hypercholesterolemia and atherosclerosis. Biomed Res Int. 2014;2014:280497. doi:10.1155/2014/280497
- Bento AP, Cominetti C, Simões Filho A, Naves MM. Baru almond improves lipid profile in mildly hypercholesterolemic subjects: a randomized, controlled, crossover study. Nutr Metab Cardiovasc Dis. 2014;24:1330. doi:10.1016/j.numecd.2014.07.002
- Hobbs T, Caso R, McMahon D, Nymark M. A novel, multi-ingredient supplement to manage elevated blood lipids in patients with no evidence of cardiovascular disease: a pilot study. Altern Ther Health Med. 2014;20:18.
